Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in adults. According to the National Cancer Society an estimated 60,000 people are living throughout the United States with CLL.

An article published in The Lancet stated that the chemotherapy combination of Fludara plus Cytoxan improves progression free survival compared to therapy consisting of Fludara alone. The drugs used to treat CLL consist of Fludara, Cytoxan and chlorambucil. Recent studies have shown that Fludara in combination with Cytoxan to be the most effective treatment for CLL.

Researchers wanted to test to see if higher anticancer responses were seen with the combination of Fludara plus Cytoxan, treatment with Fludara alone or treatment with chlorambucil.

Liver cancer experts attribute the rise in HCC, a highly aggressive cancer sometimes called hepatoma, to an increase decades ago in chronic infection with hepititis C & B and also chronic alcohol consumption. Worldwide liver cancer affects 700,000 people with 18,000 Americans diagnosed in 2006 and over 19,000 estimated to be diagnosed in 2007. The increase of this disease in the United States has doubled in one decade and over 16,000 people are estimated to die from the disease this year.

The rise in the United States is expected to increase. There are now 1.4 million people in the United States infected with HBV and 4 million are infected with HCV. Growing evidence suggests two other diseases now increasingly common in the United States to have significant risk factors for primary liver cancer. Diabetes and obesity.

HCC typically does not have any symptoms until its later stages which makes it difficult to diagnose. Traditional chemo does not treat the disease with much success and liver transplants or resection surgeries are needed. One reason why donors are very important in fighting this disease. When signs and symptoms do arise they might include weight loss, fatigue, pain in the upper right abdomen that may extend to the back and shoulder, feeling full after small meals, accumulation of fluid in the abdomen, nausea, loss of appetite, and jaundice.

Periodontitis is a chronic gum disease that progresses very slowly. It can lead to bone loss around affected teeth.

Researchers from the University at Buffalo School of Dental Medicine in New York say that those with gum disease have a higher risk of developing tongue cancer. The researchers compared 51 men diagnosed with tongue cancer to 54 cancer free men.

They reported that each millimeter reduction in bone loss was associated with a 5 fold rise in risk of tongue cancer. Seeing bone loss on the x-rays indicates the gum disease has existed for decades, making it clear that periodontitis preceded the cancer diagnosis, and not the other way around.

New research may one one day help in the diagnosis and prognosis of the nation's number four cancer killer of men and number five cancer killer of women. The killer: pancreatic cancer.

Findings from an Ohio State University study show pancreatic cancer cells may leave signs in gene-related molecules called microRNAs.

Published in The Journal of the American Medical Association, this study examined pancreatic tissue from 65 people with the disease and 42 people with chronic inflammation of the pancreas, called chronic pancreatitis.

The idea of music as a healing influence which could affect health and behavior is at least as old as the writings of Aristotle and Plato. The American Music Therapy Association (AMTA) promotes a vast amount of research exploring the benefits of music as therapy through publication of the Journal of Music Therapy, Music Therapy Perspectives and other sources. A substantial body of literature exists to support the effectiveness of music therapy.

You don't have to have a particular music ability to benefit from music therapy. No particular style of music is more therapeutic than any other. You just need to enjoy your experience. Music will lower stress and help you relax. It has been proven that it reduces acute and chronic pain. Even during child birth. It can elevate moods to counteract depression and it can counteract apprehension or fear.

So today just sit back and listen to some music, do some drumming or percussion rhythms, hum some tunes, blow on a flute or harmonica even if you don't know any particular songs. Be creative. Take advantage of the sunshine and beautiful weather and just step outside and listen to the birds, the wind, and the rhythm of mother nature. The stand by of anything else is to plug in a favorite CD and close your eyes and just let it sink in.

After several weeks of hiding and down time, a few weeks ago I made an official announcement to the non profit organization that I founded Indie Music For Life and its two entities Laughs For Life and Indiegrrl. I dropped off of this blog page for a month and am ready to write again. I needed a break. A break to sort through things. To sort through life.

When you or a loved one are diagnosed with cancer it changes your life. Finding out you have cancer takes your breath away and from that point your breath is the most valuable thing to you in your life. Breath and time. Nothing is normal any more. Not your dreams, your nightmares, and not your waking moments.

A personal diagnosis of chronic myloid leukemia in February sent me into a whirlwind of emotions. At that point, all the fear, terror, and stomach knots from my past rounds of cancer came back. Nobody free of cancer could ever appreciate how utterly devastating the news of contracting it could be and the news that it has returned is even more devastating because you know what uphill climbs you must make again. Once you have been diagnosed with cancer you always look over your shoulder for the beast to return. He has caught up with me several times now and so I am speeding up in my race trying to see who is the best long distance runner. Every ache you feel or every little un-ordinary thing that happens with your body sends you into " What If " mode. It is extremely hard living in that mode of thinking but you can't avoid it.

My past struggles with cancer were very private. But then I was not the head of a non profit organization that raises money for cancer research and educational awareness on the powers of music and laughter as therapy for cancer patients. I wasn't the head of the largest networking group of female songwriters known as Indiegrrl that has since become a part of Indie Music for Life. Laughs For Life had not even been thought of yet and now with the direction and help of good friend and comedian Shelly Ryan it is now a reality. I hadn't even started my music career. Having cancer is what lead me to pursue my career in music and chase my dreams. It wasn't until I started working on my CDs that my cancer became really public other than with my close friends and family and then working to set up the Indie Music For Life non profit put it out there even more.

United States Representative Charles Norwood, who left Washington last week to enter into the care of hospice, died yesterday at his home after battling cancer and lung disease. He was 65.

Norwood, whose passing prompted the House to observe a moment of silence Tuesday in his honor, suffered since 1998 from chronic lung disease and later metastatic cancer that spread from his lungs to his liver. Last week, he announced he would no longer accept treatment, that he would allow hospice to care for him for the remainder of his days.

A dentist from Augusta, Georgia, Norwood was the first Republican to represent northeastern Georgia since the Civil War. A conservative passionately opposed to government bureaucracy and adamantly supportive of patients' rights, he hoped to one day become Georgia's first Republican Governor.

Norwood's medical decline began when his lung condition -- idiopathic pulmonary fibrosis -- began restricting his ability to breathe and necessitated a lung transplant in 2004.

Known for zipping around the Capitol with a motorized cart and oxygen tank, Norwood developed cancer on his non-transplanted lung reportedly due to the immune suppression drugs he took after his transplant. And although his cancer was surgically removed and his health did improve, doctors learned this past November his cancer had spread.

The vacancy left by Norwood's death will not be filled immediately due to governmental process. In Georgia, within 10 days of the seat being vacated, the governor must request a special election to the secretary of state. And the election must be held no fewer than 30 days later.

Norwood is survived by his wife, Gloria; two sons, Charles and Carlton; and four grandchildren.

In the January issue of Blood, a study shows that in rare cases of chronic myelogenous leukemia (CML), treatment with Gleevec can be discontinued.

The researchers think that some patients treated with Gleevec (imatinib mesylate) that go into extended remissions can stop the drug. They add that patients continue strict monitoring for relapse.

Twelve patients were put into remission with Gleevec for over two years. Six of these patients experienced a relapse within five months after being taken off the drug. When Gleevec was restarted, residual disease again declined.

The other six patients remain in remission after nine to twenty four months follow up.

Despite these results the researchers say 'we do not widely recommend imatinib discontinuation at the present time".

I do have a few questions myself that the article did not address:

Does Gleevec have severe side effects that warrants stopping it at all?

Do they think that Gleevec can potentially cure the patient and some might be able to stop treatment all together?

Chronic myelomonocytic leukemia (CMML) is a type of leukemia that is categorized by the abnormal production or maturation of immune cells.

The drug Dacogen (decitabine) provides anticancer activity by disrupting cellular processes so that cancer cells stop growing. Although it is not currently approved for CMML, clinical trials are evaluating its effectiveness for the treatment of a variety of cancers.

A clinical trial conducted by M.D. Anderson to evaluate Dacogen in the treatment of CMML was published in the journal Cancer. Out of the 19 patients studied, 58 percent achieved a complete disappearance of detectable cancer.

The researchers did conclude that Dacogen appears to be an effective treatment option for patients diagnosed with Chronic myelomonocytic leukemia.

United States Representative Charlie Norwood will soon depart Washington, for good. He will head straight home to Georgia where he will receive hospice care now that he has decided to decline all further treatment for lung cancer that has spread to his liver.

An air ambulance will fly Norwood, 65, home as early as Wednesday or Thursday. The congressman, who had been traveling the halls of Congress in an eclectic cart, with oxygen tank in tow has spent much of his time this session in the hospital.

Suffering from chronic lung disease and idiopathic pulmonary fibrosis, Norwood received a lung transplant in 2004. Doctors then discovered a tumor on his non-transplanted lung and removed it in 2006. But the cancer had already spread to his liver. And while Norwood considered continued treatment, he ultimately determined, "No, you know what, it's time to go home."

Norwood, whose condition was acknowledged by President Bush in his last State of the Union speech, is said to have been as stubborn in his fight against cancer as he was in this fight for the legislation he thought was important for America.

The American Cancer Society has happily announced that cancer deaths have declined for the second straight year. This is big news -- mostly because our population is growing and aging and it's entirely possible this could have led to an increase in cancer deaths. Not only is this not true, but the drop in deaths for this second year is eight times greater than the drop during the first year. Amazing.

It's hard to imagine in light of this great news that there are still less hopeful statistics out there on the cancer front. But there are so many dimensions to this disease -- prevention, detection, diagnosis, treatment, survival -- that the numbers can vary tremendously depending on perspective.

From the perspective of diagnosis, one in two men and one in three women in America today will develop cancer during their lifetimes. These staggering statistics, based on data collected during 2001 through 2003, are detailed in a pivotal paper appearing in The Oncologist -- a monthly peer-reviewed journal for doctors devoted to cancer patient care.

Dr. Matthew Hayat and colleagues, who worked on this paper for the National Cancer Institute, reveal other worrisome numbers and facts.

It seems the number of new cancer patients is expected to more than double from the current 1.36 million in 2000 to almost 3 million in 2050. Five-year survival for all cancer stages combined ranges from as low as 16 percent for lung cancer patients to 100 percent for prostate cancer patients. And black Americans are reported to have the highest cancer incidence and mortality rates for men and women for all cancers combined.

So while less people are dying from cancer, diagnosis of the disease seems to be on the rise. Not exactly a perfect scenario -- but if science and research can keep up, perhaps those diagnosed with cancer will need to prepare not for death, but for the management of a chronic condition.

Health care provider Dr. Anthony Vendryes wrote Monday in the Jamaica Gleaner that he is distressed at the growing number of young women developing cancer -- especially breast cancer. He believes women are not working very hard at preventing the disease. He thinks we are just waiting for the problem to surface and then treating it with "painful and often ineffective" efforts.

According to Vendryes, research indicates a woman's risk of developing breast cancer is under her own control. If we live a lifestyle that promotes cancer, we are apparently likely to get the disease. Such a lifestyle would include gaining more than 11 pounds after the age of 18, exercising less than one time per week, eating less than five servings of fruits and vegetables per day, eating more than three ounces of red meat per day, ingesting too much fat and salt, consuming more than one alcoholic drink per day, and smoking cigarettes.

I am all for healthy living. And I believe achieving good health is under our control. I would personally recommend every woman take charge of her life in a healthful manner. But I do not believe as Vendryes states, "most women actually give themselves cancer by making poor choices in life." I think it's the word most that bothers me.

Obviously, there is a connection between lifestyle choices and chronic disease. And of course our level of health is under our control -- to some extent. But I don't believe it's fair to claim most women ask for breast cancer. I know I didn't.

I did not choose cancer. It chose me. Vendryes might say I am one of the disillusioned people who think cancer is entirely a matter of chance or entirely a matter of genetics. Actually, I suspect it's a combination of all factors. All I know for sure, however, is that my own lifestyle choices were pretty darn healthy prior to my diagnosis.

My weight has always been in a normal range -- and while I did gain more than 11 pounds twice in my life, it was due both times to the more-than-ten-pound babies I delivered into the world. I have always eaten a fairly healthy diet. I consume sweets, salt, and fats in moderation. I have never smoked and have consumed alcohol only minimally. And I have always consistently exercised.

I admit I have eaten red meat, although never daily. And I'm sure I fall short on the recommended intake of fruits and vegetables. But really, I cannot even begin to imagine that my lifestyle was an invitation for cancer. And it makes me sad that most other young women, shocked by a diagnosis of breast cancer like me, might think they asked for such a horrible disease.

It's been two years since my breast cancer diagnosis and subsequent "painful and often ineffective" treatments. And although I have made some lifestyle changes -- I never drink alcohol now, I exercise a little more, and I don't choose to eat red meat if other options are available -- my life is much the same as it was prior to cancer. And I am certain that if cancer makes a return visit to my body, it will not be because I asked for it.

It's been reported that procrastination is on the rise. Not only that, but it makes people poorer, fatter, and unhappier too.

It took 10 years of research when it was projected to take only five years -- procrastination at its best -- to come to this conclusion. And now Canadian industrial psychologist and University of Calgary professor Piers Steel is talking about his giant 30-page study that appears in this month's Psychological Bulletin.

Something must be done about this problem, says Steel, who reveals 26 percent of the American public consider themselves chronic procrastinators. This is up from five percent in 1978 and is likely due to the tempting diversions facing us in this day and age -- TVs, cell phones, video games, iPods, the Internet, and Blackberries.

It's no surprise with such temptations that a quarter of Americans say they procrastinate. When it comes to the sexes, men are worse than women -- about 54 out of 100 chronic procrastinators are men -- and the young are more like to procrastinate than the old. Three out of four college students consider themselves procrastinators. And it seems perfectionists procrastinate less because they don't like to delay.

Steel says procrastination wastes time. And it's costly too.

"The U.S. gross national product would probably rise by $50 billion if the icon and sound that notifies people of new e-mail suddenly disappear," he said.

Steel found a delay in filing taxes on average costs a person $400 a year. Last-minute Christmas shopping with credit cards was five times higher in 1999 than in 1991. Clearly, procrastination is expensive.

Procrastination also has physical and emotional costs. Procrastinators tend to be less healthy, less wealthy, and less happy. They are also harder to heal of their problems than alcoholics.

Steel, who plans to one day compare the procrastination practices in various countries and cultures, says his field has benefits. The more he knows about the problem, the less he indulges in delay tactics. He did, however, acknowledge that his study was completed five years late. But what he likes about this study is this -- "If you take a day off from it, you can always say it's field research."

Sprycel is an oral agent that has recently been approved by the FDA. It works by stopping the production of proteins involved in cancer growth.

The American Society of Hematology presented results that stated that treatment with Sprycel (dasatinib) provides better outcomes compared to giving higher doses of Gleevec (imatinib), in patients with chronic myeloid leukemia (CML), who have stopped responding to standard doses of Gleevec.

In the clinical trial the patients were either treated with Sprycel or increased doses of Gleevec to see who had the better response.

Study results indicated:

• Patients who had achieved a major anticancer response with the standard dose of Gleevec initially, achieved a 35 percent complete response to Sprycel, compared with only 7 percent of those treated with the increased doses of Gleevec.
• Patients who did not receive a major anticancer response with the standard dose of Gleevec initially, achieved a 44 percent major anticancer response to Sprycel, compared to only 7 percent of those treated with the increased doses of Gleevec.
• The main side effect of Sprycel was low levels of blood cells, which may be partly corrected with the use of Neulasta.

The research has concluded that Sprycel provides superior responses to increased-doses of Gleevec among patients with chronic-phase CML who have stopped responding to prior Gleevec therapy.

Dr. Len Lichtenfeld, MD, is the deputy chief medical officer for the American Cancer Society. He is also a blogger and authors his very own blog -- called Dr. Len's Cancer Blog.

Dr. Len writes on his blog about all sorts of topics related to cancer. He shares his opinion on the recent drop in breast cancer cases (December 15, 2006), he promotes the Great American Smokeout (November 14, 2006), he sounds off on lung cancer screenings (October 25, 2006), and he urges parents to always slather sunscreen on their children (October 5, 2006). He has so much more to say -- and his blog is a great stop for those wishing for more information on hot cancer topics.

As this year comes to a close, Dr. Len offers a review of what he believes were the hottest cancer topics of 2006.

Dr. Len reflects in his blog about decreased cancer death rates that represent real progress in the fight against cancer. He calls the HPV vaccine a breakthrough and he recaps the STAR trial -- a comparison of raloxifene to tamoxifen to reduce the risk of recurrent breast cancer in post-menopausal women -- with emphasis on how raloxifene proved just as effective as tamoxifen, but with a better safety profile. He calls new targeted therapies a dream -- with a hefty price tag -- sure to garner debate and discussion in 2007.

Dr. Len reviews the Surgeon General's report on second-hand smoke -- it's harmful to non-smokers, the report says -- and he marvels at the capability of science to approach an understanding of what makes a cancer cell a cancer cell. He also remarks on how remarkable it is that chronic myelogenous leukemia is in fact chronic and no longer fatal, thanks to the drug Gleevec.

Of course, there is ample attention given to the declining incidence of breast cancer, reportedly due to less women using hormone replacement therapy, and the risks weighing on those who are overweight and obese, and survivors and supporters who gathered for Celebration on the Hill -- the site of one incredible American Cancer Society event.

Dr. Len closes his review of 2006 with recognition of three celebrities who lost their lives this year to cancer -- Dana Reeve, Ann Richards, and Ed Bradley. And while he recognizes there are other lives and other stories that deserve mention, there is simply not enough time or space for him to do justice to every noteworthy item.

"What we have seen over the past year is an incredible leap forward in cancer research, diagnosis and treatment, and I suspect there are going to be even more exciting developments in the coming year," says Dr. Len who looks forward to 2007 -- a year that is sure to deliver more hope and more progress in the fight against cancer.